CACNB3 Polyclonal Antibody

    • 货号:YN5653
    • 应用:WB;IHC;IF
    • 种属:Mouse;Rat
      • 靶点:
      • CACNB3
      • 简介:
      • >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
      • 基因名称:
      • CACNB3
      • 蛋白名称:
      • Voltage-dependent L-type calcium channel subunit beta-3
      • Human Gene Id:
      • 784
      • Human Swiss Prot No:
      • P54284
      • Mouse Swiss Prot No:
      • P54285
      • 免疫原:
      • Synthetic Peptide of CACNB3
      • 特异性:
      • The antibody detects endogenous CACNB3 protein.
      • 组成:
      • PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-1000 IHC 1:200-500. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CACNB3;CACNLB3;Voltage-dependent L-type calcium channel subunit beta-3;CAB3;Calcium channel voltage-dependent subunit beta 3
      • 实测条带:
      • 50kD
      • 背景:
      • This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011],
      • 功能:
      • function:The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.,similarity:Belongs to the calcium channel beta subunit family.,similarity:Contains 1 SH3 domain.,subunit:The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with CACNA2D4.,tissue specificity:Expressed mostly in brain, smooth muscle and ovary.,
      • 细胞定位:
      • Cytoplasm .
      • 组织表达:
      • Expressed mostly in brain, colon and ovary.
      • 产品图片
      • Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using CACNB3 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CACNB3 Polyclonal Antibody.