CD2BP2 Polyclonal Antibody
- 货号：YT0746
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Monkey
- 蛋白名称：
- CD2 antigen cytoplasmic tail-binding protein 2
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150
- 特异性：
- CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CD2BP2;KIAA1178;CD2 antigen cytoplasmic tail-binding protein 2;CD2 cytoplasmic domain-binding protein 2;CD2 tail-binding protein 2
- 背景：
- This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],
- 功能：
- similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,
- 细胞定位：
- Cytoplasm. Nucleus. Predominantly nuclear.
- 组织表达：
- Aorta,Brain,Epithelium,Liver,Lung,
- Western Blot analysis of various cells using CD2BP2 Polyclonal Antibody diluted at 1:1000
- Western blot analysis of lysates from COS7 cells, using CD2 Tail-binding Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using CD2 Tail-binding antibody.
