• 靶点：
• IL-13Rα2

• 简介：
• >>Cytokine-cytokine receptor interaction;>>JAK-STAT signaling pathway

• 基因名称：
• IL13RA2

• 蛋白名称：
• Interleukin-13 receptor subunit alpha-2

• Human Gene Id：
• 3598

• Human Swiss Prot No：
• Q14627

• Mouse Swiss Prot No：
• O88786

• 免疫原：
• Synthesized peptide derived from Interleukin-13 receptor subunit alpha-2 at AA range: 241-290

• 特异性：
• IL-13Rα2 Polyclonal Antibody detects endogenous levels of IL-13Rα2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• IL13RA2;IL13R;Interleukin-13 receptor subunit alpha-2;IL-13 receptor subunit alpha-2;IL-13R subunit alpha-2;IL-13R-alpha-2;IL-13RA2;Interleukin-13-binding protein;CD213a2

• 实测条带：
• 44kD

• 背景：
• The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008],

• 功能：
• domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Binds as a monomer with high affinity to interleukin 13 (IL13), but not to IL4.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,similarity:Contains 1 fibronectin type-III domain.,

• 细胞定位：
• Membrane; Single-pass type I membrane protein.

• 组织表达：
• Brain,Lung,Prostate,Renal cell carcinoma,Testis,

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