Total XRCC3 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3434C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • XRCC3
    • Human Gene Id:
    • 7517
    • Human Swiss Prot No:
    • O43542
    • Mouse Swiss Prot No:
    • Q9CXE6
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:Met-241 is associated with the development of cutaneous malignant melanoma.,function:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51C and RAD51. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3.,
    • Function:
    • DNA metabolic process, DNA repair, DNA recombination, response to DNA damage stimulus, cellular response to stress,
    • Subcellular Location:
    • Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion. Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair.