14-3-3 eta Mouse mAb(5B2)

    • Catalog No.:YM3800
    • Applications:WB;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • 14-3-3 eta
      • Gene Name:
      • YWHAH YWHA1
      • Protein Name:
      • 14-3-3 eta
      • Human Gene Id:
      • 7533
      • Human Swiss Prot No:
      • Q04917
      • Mouse Swiss Prot No:
      • P68510
      • Immunogen:
      • Synthesized peptide derived from human 14-3-3 eta
      • Specificity:
      • This antibody detects endogenous levels of 14-3-3 eta at Human, Mouse,Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
      • Source:
      • Mouse,monoclonal
      • Dilution:
      • WB 1:500-2000 IHC 1:50-200
      • Purification:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • 14-3-3 protein eta (Protein AS1)
      • Observed Band(KD):
      • 28kD
      • Function:
      • function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.,similarity:Belongs to the 14-3-3 family.,subunit:Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with RGNEF and PCTK1 (By similarity). Weakly interacts with CDKN1B.,tissue specificity:Expressed mainly in the brain and present in other tissues albeit at lower levels.,
      • Expression:
      • Expressed mainly in the brain and present in other tissues albeit at lower levels.
      • Products Images
      • Ma, Zhan, Shuping Lou, and Zheng Jiang. "PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway." Aging (Albany NY) 12.9 (2020): 7985.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).