GLUT-1(PT2004) mouse mAb

    • Catalog No.:YM6634
    • Applications:IHC-p
    • Reactivity:Human
      • Gene Name:
      • SLC2A1 GLUT1
      • Protein Name:
      • Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter)
      • Human Gene Id:
      • 6513
      • Human Swiss Prot No:
      • P11166
      • Immunogen:
      • Synthesized peptide derived from human GLUT-1
      • Specificity:
      • This antibody detects endogenous levels of human Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter).
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Mouse/IgG3, Kappa
      • Dilution:
      • IHC-p 1:100-500
      • Purification:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Background:
      • solute carrier family 2 member 1(SLC2A1) Homo sapiens This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013],
      • Function:
      • disease:Defects in SLC2A1 are the cause of autosomal dominant GLUT1 deficiency syndrome [MIM:606777]; also called blood-brain barrier glucose transport defect. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.,disease:Defects in SLC2A1 are the cause of dystonia type 18 (DYT18) [MIM:612126]. DYT18 is an exercise-induced paroxysmal dystonia/dyskinesia. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYT18 is characterized by attacks of involuntary movements triggered by certain stimuli such as sudden movement or prolonged exercise. In some patients involuntary exertion-induced dystonic, choreoathetotic, and ballistic movements may be associated with macrocytic hemolytic anemia.,function:Facilitative g
      • Subcellular Location:
      • Membranous
      • Expression:
      • Articular cartilage,Brain,PCR rescued clones,
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human Colon carcinoma. 1,GLUT-1 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
      • Immunohistochemical analysis of paraffin-embedded human Placenta. 1,GLUT-1 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval