MAZ Polyclonal Antibody

    • Catalog No.:YT2669
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • MAZ
      • Gene Name:
      • MAZ
      • Protein Name:
      • Myc-associated zinc finger protein
      • Human Gene Id:
      • 4150
      • Human Swiss Prot No:
      • P56270
      • Mouse Swiss Prot No:
      • P56671
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human MAZ. AA range:159-208
      • Specificity:
      • MAZ Polyclonal Antibody detects endogenous levels of MAZ protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • MAZ;ZNF801;Myc-associated zinc finger protein;MAZI;Pur-1;Purine-binding transcription factor;Transcription factor Zif87;ZF87;Zinc finger protein 801
      • Observed Band(KD):
      • 48kD
      • Background:
      • function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,
      • Function:
      • function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,
      • Subcellular Location:
      • Nucleus . In brains of Alzheimer disease patients, present in a plaque-like structures.
      • Expression:
      • Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level). ; [Isoform 1]: Expressed in the heart, brain, placenta, lung, liver, skeletal muscle and weakly expressed in the kidney (PubMed:1502157). Expressed in the joint synovium (PubMed:19583771).
      • Products Images
      • Western blot analysis of the lysates from HepG2 cells using MAZ antibody.