SSTR4 Polyclonal Antibody
- Catalog No.:YT4430
- Applications:WB;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- SSTR4
- Fields:
- >>Neuroactive ligand-receptor interaction
- Gene Name:
- SSTR4
- Protein Name:
- Somatostatin receptor type 4
- Human Gene Id:
- 6754
- Human Swiss Prot No:
- P31391
- Mouse Swiss Prot No:
- P49660
- Rat Gene Id:
- 25555
- Rat Swiss Prot No:
- P30937
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SSTR4. AA range:155-204
- Specificity:
- SSTR4 Polyclonal Antibody detects endogenous levels of SSTR4 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- SSTR4;Somatostatin receptor type 4;SS-4-R;SS4-R;SS4R
- Observed Band(KD):
- 42kD
- Background:
- Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. [provided by RefSeq, Jul 2008],
- Function:
- function:Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.,
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
- Expression:
- Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from LOVO cells, using SSTR4 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HepG2 cells using SSTR4 antibody.