Flt3-L Polyclonal Antibody

    • Catalog No.：YT5516
    • Applications：WB;ELISA
    • Reactivity：Human;Mouse
      • Target：
      • Flt3-L
      • Fields：
      • >>MAPK signaling pathway;>>Ras signaling pathway;>>PI3K-Akt signaling pathway;>>Hematopoietic cell lineage;>>Pathways in cancer
      • Gene Name：
      • FLT3LG
      • Protein Name：
      • Fms-related tyrosine kinase 3 ligand
      • Human Gene Id：
      • 2323
      • Human Swiss Prot No：
      • P49771
      • Mouse Swiss Prot No：
      • P49772
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from the C-terminal region of human FLT3LG. AA range:171-220
      • Specificity：
      • Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • FLT3LG;Fms-related tyrosine kinase 3 ligand;Flt3 ligand;Flt3L;SL cytokine
      • Observed Band(KD)：
      • 26kD
      • Background：
      • Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],
      • Function：
      • function:Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins.,subunit:Homodimer (isoform 2).,
      • Subcellular Location：
      • [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
      • Expression：
      • Brain,Spleen,
      • Products Images
      • Western Blot analysis of HeLa cells using Flt3-L Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

      Attributes

      • Code：
      • YT5516
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-11-24
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