RFA1 rabbit pAb
- Catalog No.:YT7984
- Applications:WB;ELISA;IHC
- Reactivity:Human;Monkey;Mouse;Rat
- Target:
- RFA1
- Fields:
- >>DNA replication;>>Nucleotide excision repair;>>Mismatch repair;>>Homologous recombination;>>Fanconi anemia pathway
- Gene Name:
- RPA1 REPA1 RPA70
- Protein Name:
- RFA1
- Human Gene Id:
- 6117
- Human Swiss Prot No:
- P27694
- Mouse Gene Id:
- 68275
- Mouse Swiss Prot No:
- Q8VEE4
- Immunogen:
- Synthesized peptide derived from human RFA1
- Specificity:
- This antibody detects endogenous levels of Human,Monkey,Mouse,Rat RFA1
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Replication protein A 70 kDa DNA-binding subunit (RP-A p70;Replication factor A protein 1;RF-A protein 1;Single-stranded DNA-binding protein)
- Molecular Weight(Da):
- 68kD
- Background:
- function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
- Function:
- function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
- Subcellular Location:
- Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).