IGF-1 Rabbit pAb
-YT2288
主要信息
Target
IGF-I
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
Conjugate/Modification
Unmodified
货号: YT2288
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
IGF-I Polyclonal Antibody detects endogenous levels of IGF-I protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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β-actin (PTR2364) Mouse mAb
YM3028
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GAPDH (PTR2304) Mouse mAb
YM3029
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human IGF-I. AA range:100-149
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特异性:
IGF-I Polyclonal Antibody detects endogenous levels of IGF-I protein.
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基因名称:
IGF1 IBP1
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蛋白名称:
Insulin-like growth factor I
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别名:
IBP1 ;
IGF-IA ;
IGF1A ;
IGFI ;
insulin-like growth factor 1 ;
insulin-like growth factor IA ;
mechano growth factor ;
MGF ;
somatomedin C
IGF-IA ;
IGF1A ;
IGFI ;
insulin-like growth factor 1 ;
insulin-like growth factor IA ;
mechano growth factor ;
MGF ;
somatomedin C
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背景:
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor , bound by a specific receptor , and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq , Sep 2015] ,
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功能:
Disease:Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation , sensorineural deafness and mental retardation. ,Function:The insulin-like growth factors , isolated from plasma , are structurally and functionally related to insulin but have a much higher growth-promoting activity. ,online information:Insulin-like growth factor 1 entry ,online information:The Singapore human mutation and polymorphism database ,similarity:Belongs to the insulin family. ,
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细胞定位:
extracellular region ,extracellular space ,plasma membrane ,insulin-like growth factor binding protein complex ,platelet alpha granule lumen ,alphav-beta3 integrin-IGF-1-IGF1R complex ,insulin-like growth factor ternary complex ,exocytic vesicle ,
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组织表达:
信号通路
Cellular Processes >> Cell growth and death >> p53 signaling pathway
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells
Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action
Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels
Organismal Systems >> Aging >> Longevity regulating pathway
Organismal Systems >> Aging >> Longevity regulating pathway - multiple species
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Cancer: specific types >> Glioma
Human Diseases >> Cancer: specific types >> Melanoma
Human Diseases >> Cancer: specific types >> Prostate cancer
Human Diseases >> Cancer: specific types >> Breast cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway
Environmental Information Processing >> Signal transduction >> FoxO signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signal transduction >> AMPK signaling pathway
Environmental Information Processing >> Signal transduction >> mTOR signaling pathway
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货号: YT2288
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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