GAPDH (PTR2304) Mouse mAb
-YM3029
主要信息
Target
GAPDH
Host Species
Mouse
Reactivity
Human, Mouse, Rat, Dog, Monkey, Rabbit, Pig, Bovine
Applications
WB, IF, ELISA
MW
38kD (Calculated)
38kD (Observed)
Conjugate/Modification
Unmodified
货号: YM3029
规格
价格
货期
数量
1mL
￥6,800.00
现货
0
500μL
￥4,000.00
现货
0
100μL
￥920.00
现货
0
加入购物车
已收藏
收藏
偶联抗体
GAPDH (2B8) Mouse mAb (AbFluor 350)
GAPDH (2B8) Mouse mAb (AbFluor 405)
GAPDH (2B8) Mouse mAb (AbFluor 488)
GAPDH (2B8) Mouse mAb (AbFluor 555)
GAPDH (2B8) Mouse mAb (AbFluor 594)
GAPDH (2B8) Mouse mAb (AbFluor 647)
GAPDH (2B8) Mouse mAb (AbFluor 680)
GAPDH (2B8) Mouse mAb (Biotin)
GAPDH (2B8) Mouse mAb (Cy3)
GAPDH (2B8) Mouse mAb (Cy5)
GAPDH (2B8) Mouse mAb (FITC)
GAPDH (2B8) Mouse mAb (HRP)
详细信息
推荐稀释比
WB 1:10000-50000; IF 1:100-500; ELISA 1:50000-500000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
This antibody detects endogenous levels of GAPDH protein.
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
理论分子量
38kD
实测条带
38kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PTR2304
同种型
IgG1, Kappa
RRID号
AB_3683541
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthetic Peptide of human GAPDH AA range: 200-300
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特异性:
This antibody detects endogenous levels of GAPDH protein.
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基因名称:
GAPDH
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蛋白名称:
Glyceraldehyde-3-phosphate dehydrogenase
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别名:
GAPDH ;
GAPD ;
CDABP0047 ;
OK/SW-cl.12 ;
Glyceraldehyde-3-phosphate dehydrogenase ;
GAPDH ;
Peptidyl-cysteine S-nitrosylase GAPDH
GAPD ;
CDABP0047 ;
OK/SW-cl.12 ;
Glyceraldehyde-3-phosphate dehydrogenase ;
GAPDH ;
Peptidyl-cysteine S-nitrosylase GAPDH
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背景:
glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism , the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also , this protein contains a peptide that has antimicrobial activity against E. coli , P. aeruginosa , and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins , the regulation of mRNA stability , and acting as a transferri
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功能:
Catalytic activity:D-glyceraldehyde 3-phosphate + phosphate + NAD (+) = 3-phospho-D-glyceroyl phosphate + NADH. ,Function:Independent of its glycolytic activity it is also involved in membrane trafficking in the early secretory pathway. ,online information:Glyceraldehyde 3-phosphate dehydrogenase entry ,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1. ,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5. ,PTM:Reversible S-nitrosylation of Cys-152 inhibits enzymatic activity and increases endogenous ADP-ribosylation , which inhibits the enzyme in a non-reversible manner. The latter modification is more likely to be a pathophysiological event associated with inhibition of gluconeogenesis. ,sequence Caution:Differs quite extensively. ,similarity:Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. ,subcellular location:Postnuclear and Perinuclear regions. ,subunit:Homotetramer. ,subunit:Homotetramer. Binds PRKCI. ,
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研究领域:
>>Glycolysis / Gluconeogenesis ;
>>Metabolic pathways ;
>>Carbon metabolism ;
>>Biosynthesis of amino acids ;
>>HIF-1 signaling pathway ;
>>Alzheimer disease ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection ;
>>Diabetic cardiomyopathy
>>Metabolic pathways ;
>>Carbon metabolism ;
>>Biosynthesis of amino acids ;
>>HIF-1 signaling pathway ;
>>Alzheimer disease ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection ;
>>Diabetic cardiomyopathy
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信号通路
文献引用（{{totalcount}}）
货号: YM3029
规格
价格
货期
数量
1mL
￥6,800.00
现货
0
500μL
￥4,000.00
现货
0
100μL
￥920.00
现货
0
加入购物车
已收藏
收藏
偶联抗体
GAPDH (2B8) Mouse mAb (AbFluor 350)
GAPDH (2B8) Mouse mAb (AbFluor 405)
GAPDH (2B8) Mouse mAb (AbFluor 488)
GAPDH (2B8) Mouse mAb (AbFluor 555)
GAPDH (2B8) Mouse mAb (AbFluor 594)
GAPDH (2B8) Mouse mAb (AbFluor 647)
GAPDH (2B8) Mouse mAb (AbFluor 680)
GAPDH (2B8) Mouse mAb (Biotin)
GAPDH (2B8) Mouse mAb (Cy3)
GAPDH (2B8) Mouse mAb (Cy5)
GAPDH (2B8) Mouse mAb (FITC)
GAPDH (2B8) Mouse mAb (HRP)
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