Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CCL3

C-C motif chemokine 3

CCL3 ;
G0S19-1 ;
MIP1A ;
SCYA3 ;
C-C motif chemokine 3 ;
G0/G1 switch regulatory protein 19-1 ;
Macrophage inflammatory protein 1-alpha ;
MIP-1-alpha ;
PAT 464.1 ;
SIS-beta ;
Small-inducible cytokine A3 ;
Tonsillar lymphocyte LD78 alpha protein

function:Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).,induction:By TPA or PHA (TPA = 12-O-tetradecanoyl phorbol-13 acetate (tumor promoter); PHA = phytohemagglutinin (T-cell mitogen)).,online information:Macrophage inflammatory protein entry,PTM:N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Self-associates. Also heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69).,

cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, exocytosis, cell motion,chemotaxis, defense response, inflammatory response, immune response, cytoskeleton organization, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, cell-cell signaling, behavior,locomotory behavior, response to wounding, vesicle-mediated transport, cellular homeostasis, cellular cation homeostasis, cellular di-, tri-valent inorganic cation homeostasis, secretion by cell, taxis, homeostatic process,regulation of viral genome replication, secretion, chemical homeostasis, regulation of viral reproduction, ion homeostasis, metal ion homeostasis, di-, tri-valent inorganic cation homeostasis, calcium ion homeostasis, cation homeostasis, cellular chemical homeostasis,

Secreted.