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CD16 (PN0398) Nb-FC recombinant antibody

-YA0651

2
主要信息
Target

CD16

Reactivity

Human

Applications

ELISA, Flow Cyt

Conjugate/Modification

Unmodified

货号: YA0651
规格
价格
货期
数量
200μg
¥3,780.00
现货

0

100μg
¥2,300.00
现货

0

40μg
¥960.00
现货

0

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详细信息
推荐稀释比
ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
组成
Phosphate-buffered solution
来源
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
特异性
This recombinant monoclonal antibody can detects endogenous levels of CD16 protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度
Please check the information on the tube
修饰
Unmodified
克隆号
PN0398
相关产品
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Goat Anti Mouse IgG(H+L) (HRP)
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抗原&靶点信息
免疫原:
Purified recombinant Human CD16
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特异性:
This recombinant monoclonal antibody can detects endogenous levels of CD16 protein.
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基因名称:
FCGR3A CD16A FCG3 FCGR3 IGFR3
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蛋白名称:
Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
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别名:
CD 16 antibody ;
CD 16a antibody ;
CD16 antibody ;
CD16a antibody ;
CD16a antigen antibody ;
CD16B antibody ;
CD16b antigen antibody ;
Fc fragment of IgG antibody ;
Fc fragment of IgG low affinity IIIa receptor ;
CD16 ;
antibody ;
Fc fragment of IgG low affinity IIIa receptor antibody ;
Fc fragment of IgG receptor IIIa antibody ;
Fc fragment of IgG ;
low affinity III ;
receptor ;
CD16 ;
antibody ;
Fc fragment of IgG ;
low affinity III ;
receptor for ;
CD16 ;
antibody ;
Fc fragment of IgG ;
low affinity IIIa ;
receptor ;
CD16 ;
antibody ;
Fc fragment of IgG ;
low affinity IIIa ;
receptor ;
CD16a ;
antibody ;
Fc fragment of IgG ;
low affinity IIIa ;
receptor for antibody ;
Fc fragment of IgG ;
low affinity IIIb ;
receptor ;
CD16b ;
antibody ;
Fc fragment of IgG ;
low affinity IIIb ;
receptor for ;
CD16 ;
antibody ;
Fc gamma R3 antibody ;
Fc gamma receptor III 2 ;
CD 16 ;
antibody ;
Fc gamma receptor III A antibody ;
Fc gamma receptor IIIA antibody ;
Fc gamma receptor IIIb ;
CD 16 ;
antibody ;
Fc gamma RIII alpha antibody ;
Fc gamma RIII antibody ;
Fc gamma RIII beta antibody ;
Fc gamma RIIIa antibody ;
Fc gamma RIIIb antibody ;
Fc of IgG antibody ;
Fc-gamma receptor III2 ;
CD 16 ;
antibody ;
Fc-gamma receptor III2 ;
CD16 ;
antibody ;
Fc-gamma receptor IIIb ;
CD16 ;
antibody ;
Fc-gamma RIII antibody ;
Fc-gamma RIII-alpha antibody ;
Fc-gamma RIIIa antibody ;
FCG 3 antibody ;
FCG3 antibody ;
FCG3A_HUMAN antibody ;
FCgammaRIIIA antibody ;
FCGR 3 antibody ;
FCGR 3A antibody ;
FCGR3 antibody ;
FCGR3A antibody ;
FCGR3A protein antibody ;
FCGRIII antibody ;
FCGRIII-2 antibody ;
FcR 10 antibody ;
FcR-10 antibody ;
FcR10 antibody ;
FcRIII antibody ;
FcRIIIa antibody ;
IGFR 3 antibody ;
IGFR3 antibody ;
IgG Fc receptor III 1 antibody ;
IgG Fc receptor III 2 antibody ;
IgG Fc receptor III-2 antibody ;
IMD20 antibody ;
immunoglobulin G Fc receptor III antibody ;
immunoglobulin G Fc receptor III-2 antibody ;
Low affinity IIIa receptor antibody ;
Low affinity immunoglobulin gamma Fc region receptor III A antibody ;
Low affinity immunoglobulin gamma Fc region receptor III-A antibody ;
Low affinity immunoglobulin gamma Fc region receptor IIIB antibody ;
neutrophil-specific antigen NA antibody ;
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数据库链接:
Organism 基因 ID SwissProt
Human 2214; P08637;
背景:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses.This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded byThis gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations inThis gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq,
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功能:
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.,miscellaneous:Encoded by one of two nearly indentical genes: FCGR3A (Shown here) and FCGR3B which are expressed in a tissue-specific manner. The Phe-203 in III-A determines the transmembrane domains whereas the Ser-203 in III-B determines the GPI-anchoring.,online information:FCGR3A mutation db,polymorphism:Isoform Val-157 shows a higher binding capacity of IgG1, IgG3 and IgG4 compared with isoform Phe-157. Alleles Leu-66 and Phe-157, and alleles His-66 / Arg-66 and Val-157 are in linkage desequilibrium.,PTM:Glycosylated. Contains high mannose- and complex-type oligosaccharides.,PTM:The soluble form is produced by a proteolytic cleavage.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Exists also as a soluble receptor.,subunit:Exists as a hetero-oligomeric receptor complex with Fc epsilon receptor I gamma subunit and / or the CD3 zeta subunit. Interacts with INPP5D/SHIP1.,tissue specificity:Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein . Secreted . Exists also as a soluble receptor. .
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组织表达:
Expressed in natural killer cells (at protein level) (PubMed:2526846). Expressed in a subset of circulating monocytes (at protein level) (PubMed:2767158).
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货号: YA0651
规格
价格
货期
数量
200μg
¥3,780.00
现货

0

100μg
¥2,300.00
现货

0

40μg
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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