联系我们

400-8787-807

快速订购
R

HRAS (PT0590R) PT® Rabbit mAb

-YM8401

hot 5
主要信息
Target

HRAS

Host Species

Rabbit

Reactivity

Human, Mouse, Rat,

Applications

WB, IHC, IF, IP, ELISA

MW

21kD (Calculated)

21kD (Observed)

Conjugate/Modification

Unmodified

货号: YM8401
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询
详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
21kD
实测条带
21kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0590R
同种型
IgG,Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001

预览→

Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002

预览→

Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028

预览→

Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029

预览→

抗原&靶点信息
特异性:
Endogenous
展开内容
基因名称:
HRAS,HRAS1
展开内容
蛋白名称:
GTPase,H-Ras-1,Ha-Ras,Transforming protein p21, ,c-H-ras, p21ras, Cleaved into: GTPase HRas N-terminally processed,Cleaved into: GTPase Hras,GTPase Hras,HRAS 1,
展开内容
别名:
HRAS,HRAS1,GTPase,H-Ras-1,Ha-Ras,Transforming protein p21, ,c-H-ras, p21ras, Cleaved into: GTPase HRas N-terminally processed,Cleaved into: GTPase Hras,GTPase Hras,HRAS 1,
展开内容
数据库链接:
Organism 基因 ID SwissProt
Human 3265; P01112;
背景:
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
展开内容
功能:
Involved in the activation of Ras protein signal transduction ,PubMed:22821884,. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity
展开内容
细胞定位:
Cytoplasm, Membrane
展开内容
组织表达:
Widely expressed. {ECO:0000269|PubMed:14500341}.
展开内容
信号通路
Cellular Processes >> Transport and catabolism >> Autophagy - animal Cellular Processes >> Transport and catabolism >> Mitophagy - animal Cellular Processes >> Cell growth and death >> Apoptosis Cellular Processes >> Cell growth and death >> Cellular senescence Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion Cellular Processes >> Cellular community - eukaryotes >> Gap junction Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity Organismal Systems >> Immune system >> T cell receptor signaling pathway Organismal Systems >> Immune system >> B cell receptor signaling pathway Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway Organismal Systems >> Immune system >> Chemokine signaling pathway Organismal Systems >> Endocrine system >> Insulin signaling pathway Organismal Systems >> Endocrine system >> GnRH signaling pathway Organismal Systems >> Endocrine system >> Estrogen signaling pathway Organismal Systems >> Endocrine system >> Prolactin signaling pathway Organismal Systems >> Endocrine system >> Oxytocin signaling pathway Organismal Systems >> Endocrine system >> Relaxin signaling pathway Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway Organismal Systems >> Nervous system >> Cholinergic synapse Organismal Systems >> Nervous system >> Neurotrophin signaling pathway Organismal Systems >> Aging >> Longevity regulating pathway Organismal Systems >> Aging >> Longevity regulating pathway - multiple species Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Cancer: overview >> MicroRNAs in cancer Human Diseases >> Cancer: overview >> Central carbon metabolism in cancer Human Diseases >> Cancer: overview >> PD-L1 expression and PD-1 checkpoint pathway in cancer Human Diseases >> Cancer: specific types >> Colorectal cancer Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma Human Diseases >> Cancer: specific types >> Gastric cancer Human Diseases >> Cancer: specific types >> Glioma Human Diseases >> Cancer: specific types >> Thyroid cancer Human Diseases >> Cancer: specific types >> Acute myeloid leukemia Human Diseases >> Cancer: specific types >> Chronic myeloid leukemia Human Diseases >> Cancer: specific types >> Melanoma Human Diseases >> Cancer: specific types >> Renal cell carcinoma Human Diseases >> Cancer: specific types >> Bladder cancer Human Diseases >> Cancer: specific types >> Prostate cancer Human Diseases >> Cancer: specific types >> Endometrial cancer Human Diseases >> Cancer: specific types >> Breast cancer Human Diseases >> Cancer: specific types >> Non-small cell lung cancer Human Diseases >> Neurodegenerative disease >> Alzheimer disease Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases Environmental Information Processing >> Signal transduction >> MAPK signaling pathway Environmental Information Processing >> Signal transduction >> ErbB signaling pathway Environmental Information Processing >> Signal transduction >> Ras signaling pathway Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway Environmental Information Processing >> Signal transduction >> VEGF signaling pathway Environmental Information Processing >> Signal transduction >> Apelin signaling pathway Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway Environmental Information Processing >> Signal transduction >> FoxO signaling pathway Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway Environmental Information Processing >> Signal transduction >> mTOR signaling pathway
货号: YM8401
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

筛选器:

{{item.descr}}

主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
查看产品详情
产品 {{index}}/{{pcount}}
上一个产品
下一个产品

{{pvTitle}}

滚轮缩放图片
{{pvDescr}}