Clathrin Heavy Chain (PT0347R) PT® Rabbit mAb
-YM8462
主要信息
Target
CLH1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat,
Applications
WB, IHC, IF, ELISA
MW
192kD (Calculated)
180kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8462
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:50-200; WB 1:500-1:2000; IF 1:200-1000; ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
192kD
实测条带
180kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0347R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
CLTC CLH17 CLTCL2 KIAA0034
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蛋白名称:
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
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背景:
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008],
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功能:
Function:Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.,online information:Clathrin entry,similarity:Belongs to the clathrin heavy chain family.,subcellular location:Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat. In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Interacts with HIP1.,
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细胞定位:
Cytoplasm
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组织表达:
Bone marrow,Brain,Cervix carcinoma,Colon,Epithelium,Fetal kidney,Hepatoma,Mammary c
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研究领域:
>>Lysosome ;
>>Endocytosis ;
>>Synaptic vesicle cycle ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Huntington disease ;
>>Bacterial invasion of epithelial cells
>>Endocytosis ;
>>Synaptic vesicle cycle ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Huntington disease ;
>>Bacterial invasion of epithelial cells
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信号通路
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货号: YM8462
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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