Yes1 (PT0670R) PT® Rabbit mAb
-YM8560
主要信息
Target
c-Yes
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, IF, IP, ELISA
MW
61kD (Calculated)
61kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8560
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
61kD
实测条带
61kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0670R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
YES1
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蛋白名称:
Proto-oncogene tyrosine-protein kinase Yes
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别名:
YES1 ;
YES ;
Tyrosine-protein kinase Yes ;
Proto-oncogene c-Yes ;
p61-Yes
YES ;
Tyrosine-protein kinase Yes ;
Proto-oncogene c-Yes ;
p61-Yes
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背景:
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,Function:Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.,
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细胞定位:
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway.
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组织表达:
Expressed in the epithelial cells of renal proximal tubules and stomach as well as hematopoietic cells in the bone marrow and spleen in the fetal tissues. In adult, expressed in epithelial cells of the renal proximal tubules and present in keratinocytes in the basal epidermal layer of epidermis.
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研究领域:
>>Adherens junction
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文献引用（{{totalcount}}）
货号: YM8560
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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