SAPAP1 Monoclonal Antibody

    • 货号:YM0574
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human
      • 靶点:
      • SAPAP1
      • 简介:
      • >>Glutamatergic synapse
      • 基因名称:
      • DLGAP1
      • 蛋白名称:
      • Disks large-associated protein 1
      • Human Gene Id:
      • 9229
      • Human Swiss Prot No:
      • O14490
      • Mouse Swiss Prot No:
      • Q9D415
      • 免疫原:
      • Purified recombinant fragment of human SAPAP1 expressed in E. Coli.
      • 特异性:
      • SAPAP1 Monoclonal Antibody detects endogenous levels of SAPAP1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Monoclonal, Mouse
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • Affinity purification
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • DLGAP1;DAP1;GKAP;Disks large-associated protein 1;DAP-1;Guanylate kinase-associated protein;hGKAP;PSD-95/SAP90-binding protein 1;SAP90/PSD-95-associated protein 1;SAPAP1
      • 分子量:
      • 109kD
      • 背景:
      • function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,
      • 功能:
      • function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,
      • 细胞定位:
      • Cell membrane ; Peripheral membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse .
      • 组织表达:
      • Expressed in brain.
      • 产品图片
      • Western Blot analysis using SAPAP1 Monoclonal Antibody against HEK293 (1) and GKAP-hIgGFc transfected HEK293 (2) cell lysate.
      • Immunohistochemistry analysis of paraffin-embedded human liver cancer tissues with DAB staining using SAPAP1 Monoclonal Antibody.
      • Immunofluorescence analysis of NIH/3T3 cells using SAPAP1 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.