- 靶点：
- RRAD
- 基因名称：
- RRAD RAD
- 蛋白名称：
- GTP-binding protein RAD (RAD1) (Ras associated with diabetes)
- Human Gene Id：
- 6236
- Human Swiss Prot No：
- P55042
- Mouse Gene Id：
- 0
- Mouse Swiss Prot No：
- O88667
- 免疫原：
- Synthesized peptide derived from human protein. AA range: 1-100
- 特异性：
- This antibody detects endogenous levels of RRAD protein.
- 组成：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源：
- Mouse, Monoclonal/IgG1, kappa
- 稀释：
- WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
- 纯化工艺：
- Protein G
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- GTP-binding protein RAD (RAD1) (Ras associated with diabetes)
- 分子量：
- 33kD
- 实测条带：
- 33kD
- 功能：
- May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
- 细胞定位：
- Membranous
- 组织表达：
- Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
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- 产品图片
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- Whole cell lysates of A431 were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GSK3β(PTR2553) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: A431
.jpg)
- Whole cell lysates of A431 were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GSK3β(PTR2553) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: A431
- Whole cell lysates of Hela were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GSK3β(PTR2553) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: Hela
