- 靶点:
- L-type Ca++ CP γ4
- 简介:
- >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
- 基因名称:
- CACNG4
- 蛋白名称:
- Voltage-dependent calcium channel gamma-4 subunit
- Human Gene Id:
- 27092
- Human Swiss Prot No:
- Q9UBN1
- Mouse Swiss Prot No:
- Q9JJV4
- Rat Swiss Prot No:
- Q8VHW9
- 免疫原:
- Synthetic Peptide of L-type Ca++ CP γ4 AA range: 120-200
- 特异性:
- The antibody detects endogenous L-type Ca++ CP γ4 protein.
- 组成:
- PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:1000-2000 IHC 1:200-500. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CACNG4;Voltage-dependent calcium channel gamma-4 subunit;Neuronal voltage-gated calcium channel gamma-4 subunit;Transmembrane AMPAR regulatory protein gamma-4;TARP gamma-4
- 实测条带:
- 35kD
- 背景:
- calcium voltage-gated channel auxiliary subunit gamma 4(CACNG4) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],
- 功能:
- function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,
- 细胞定位:
- Cell membrane ; Multi-pass membrane protein .
- 组织表达:
- Detected in heart left ventricle.
Role of Epstein-Barr Virus and Human Papillomavirus Coinfection in Cervical Intraepithelial Neoplasia in Chinese Women Living With HIV. Frontiers in Cellular and Infection Microbiology Front Cell Infect Mi. 2021 Sep;0:847 IF Human Cervical tissues
货号:YN5521
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- Antibody-FAQs
- 产品图片
- Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using L-type Ca++ CP γ4 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using L-type Ca++ CP γ4 Polyclonal Antibody.