IGF-I Polyclonal Antibody

    • 货号:YT2288
    • 应用:IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • IGF-I
      • 基因名称:
      • IGF1
      • 蛋白名称:
      • Insulin-like growth factor I
      • Human Gene Id:
      • 3479
      • Human Swiss Prot No:
      • P05019
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human IGF-I. AA range:100-149
      • 特异性:
      • IGF-I Polyclonal Antibody detects endogenous levels of IGF-I protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • IBP1;IGF-IA;IGF1A;IGFI;insulin-like growth factor 1;insulin-like growth factor IA;mechano growth factor;MGF;somatomedin C
      • 分子量:
      • 17-22kD
      • 背景:
      • The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015],
      • 功能:
      • disease:Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.,function:The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.,online information:Insulin-like growth factor 1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the insulin family.,
      • 细胞定位:
      • extracellular region,extracellular space,plasma membrane,insulin-like growth factor binding protein complex,platelet alpha granule lumen,alphav-beta3 integrin-IGF-1-IGF1R complex,insulin-like growth factor ternary complex,exocytic vesicle,
      • 组织表达:
      • Brain,Liver,PCR rescued clones,

      Mechanism of NO2-induced migraine in rats: The exploration of the role of miR-653-3p/IGF1 axis JOURNAL OF HAZARDOUS MATERIALS Shuzi Ye WB,IF Rat 1:1000,1:500 trigeminal ganglion primary trigeminal ganglion neurons (PTGNs)
      货号:YT2288

      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded Human pancreas. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Immunohistochemistry analysis of IGF-I antibody in paraffin-embedded human pancreas tissue.