• 靶点：
• SV2C

• 简介：
• >>ECM-receptor interaction

• 基因名称：
• SV2C

• 蛋白名称：
• Synaptic vesicle glycoprotein 2C

• Human Gene Id：
• 22987

• Human Swiss Prot No：
• Q496J9

• Mouse Gene Id：
• 75209

• Mouse Swiss Prot No：
• Q69ZS6

• Rat Gene Id：
• 29643

• Rat Swiss Prot No：
• Q9Z2I6

• 免疫原：
• Synthesized peptide derived from the Internal region of human SV2C. AA range 330-390

• 特异性：
• SV2C Polyclonal Antibody detects endogenous levels of SV2C protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SV2C;KIAA1054;Synaptic vesicle glycoprotein 2C

• 实测条带：
• 82kD

• 背景：
• function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner.,

• 功能：
• function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner.,

• 细胞定位：
• Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. .

• 组织表达：
• Brain,

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