• 靶点：
• CD232

• 简介：
• >>Axon guidance

• 基因名称：
• PLXNC1

• 蛋白名称：
• Plexin-C1

• Human Gene Id：
• 10154

• Human Swiss Prot No：
• O60486

• Mouse Gene Id：
• 54712

• Mouse Swiss Prot No：
• Q9QZC2

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human PLXNC1. AA range:811-860

• 特异性：
• CD232 Polyclonal Antibody detects endogenous levels of CD232 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PLXNC1;VESPR;Plexin-C1;Virus-encoded semaphorin protein receptor;CD232

• 实测条带：
• 175kD

• 背景：
• This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011],

• 功能：
• function:Receptor for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of viral semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.,PTM:N-glycosylated.,similarity:Belongs to the plexin family.,similarity:Contains 1 Sema domain.,tissue specificity:Detected in heart, brain, lung, spleen and placenta.,

• 细胞定位：
• Membrane ; Single-pass type I membrane protein .

• 组织表达：
• Detected in heart, brain, lung, spleen and placenta.

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