CMTM8 Polyclonal Antibody
- 货号:YT5728
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- CKLF-like MARVEL transmembrane domain-containing protein 8
- 免疫原:
- The antiserum was produced against synthesized peptide derived from the Internal region of human CMTM8. AA range:101-150
- 特异性:
- CMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CMTM8;CKLFSF8;CKLF-like MARVEL transmembrane domain-containing protein 8;Chemokine-like factor superfamily member 8
- 背景:
- This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
- 功能:
- similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in liver and pancreas.,
- 细胞定位:
- [Isoform 1]: Membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm. Nucleus.
- 组织表达:
- Highly expressed in liver and pancreas.
![](/uploadfiles/PIC/yt5728wb41657.jpg)
- Western blot analysis of hela lysis using CMTM8 antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
![](/uploadfiles/PIC/yt5728ihchuman-tonsils(2).jpg)
- Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:200
![](/uploadfiles/PIC/yt5728ihchuman-tonsils.jpg)
- Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:200