Cleaved-Caspase-5 p10 (S331) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3938C
- Applications:ELISA
- Reactivity:Human;
- Gene Name:
- CASP5
- Protein Name:
- Caspase5
- Human Gene Id:
- 838
- Human Swiss Prot No:
- P51878
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Caspase-5 (CASP-5) (EC 3.4.22.58) (ICE(rel)-III) (Protease ICH-3) (Protease TY) [Cleaved into: Caspase-5 subunit p20;Caspase-5 subunit p10]
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.,function:Mediator of programmed cell death (apoptosis).,PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunits.,tissue specificity:Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.,
- Function:
- proteolysis, apoptosis, cell death, regulation of cell death, programmed cell death, death, regulation of apoptosis,regulation of programmed cell death,
- Expression:
- Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
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