CD223/LAG-3 (PN0565) Nb-FC recombinant antibody

  • Catalog No.：YA0191
  • Applications：ELISA
  • Reactivity：Human
    • Target：
    • CD223/LAG-3
    • Gene Name：
    • LAG3 FDC
    • Protein Name：
    • Lymphocyte activation gene 3 protein (LAG-3) (CD antigen CD223) [Cleaved into: Secreted lymphocyte activation gene 3 protein (sLAG-3)]
    • Human Gene Id：
    • 3902
    • Human Swiss Prot No：
    • P18627
    • Immunogen：
    • Purified recombinant Human CD223
    • Specificity：
    • This recombinant monoclonal antibody can detects endogenous levels of CD223/LAG-3 protein.
    • Formulation：
    • Phosphate-buffered solution
    • Source：
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution：
    • ELISA 1:5000-100000
    • Purification：
    • Recombinant Expression and Affinity purified
    • Concentration：
    • Please check the information on the tube
    • Storage Stability：
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name：
    • LAG3;FDC;Lymphocyte activation gene 3 protein;LAG-3;Protein FDC;CD223;CD223 nanobody;LAG-3 nanobody
    • Background：
    • Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
    • Function：
    • Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes.,
    • Subcellular Location：
    • [Lymphocyte activation gene 3 protein]: Cell membrane ; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. .
    • Expression：
    • Primarily expressed in activated T-cells and a subset of natural killer (NK) cells.

    Attributes

    • Code：
    • YA0191
    • Size
    • 40μg / 100μg / 200μg
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2025-01-24
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