CD25 (PN0487) Nb-FC recombinant antibody

  • Catalog No.:YA0204
  • Applications:ELISA
  • Reactivity:Human
    • Target:
    • CD25
    • Gene Name:
    • IL2RA
    • Protein Name:
    • Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25)
    • Human Gene Id:
    • 3559
    • Human Swiss Prot No:
    • P01589
    • Immunogen:
    • Purified recombinant Human CD25
    • Specificity:
    • This recombinant monoclonal antibody can detects endogenous levels of CD25 protein.
    • Formulation:
    • Phosphate-buffered solution
    • Source:
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution:
    • ELISA 1:5000-100000
    • Purification:
    • Recombinant Expression and Affinity purified
    • Concentration:
    • Please check the information on the tube
    • Storage Stability:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name:
    • IL2RA;Interleukin-2 receptor subunit alpha;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;CD25;CD25 nanobody;
    • Background:
    • The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations inThis gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
    • Function:
    • disease:Genetic variations in IL2RA are associated with susceptibility to insulin-dependent diabetes mellitus type 10 (IDDM10) [MIM:601942].,Receptor for interleukin-2.,online information:IL2RA mutation db,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta chain), and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain.,
    • Subcellular Location:
    • Membrane; Single-pass type I membrane protein.
    • Expression:
    • Thymus