CD27 (PN0505) Nb-FC recombinant antibody
- Catalog No.:YA0225
- Applications:FCM;ELISA
- Reactivity:Human
- Target:
- CD27
- Gene Name:
- CD27 TNFRSF7
- Protein Name:
- CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
- Human Gene Id:
- 939
- Human Swiss Prot No:
- P26842
- Immunogen:
- Purified recombinant Human CD27
- Specificity:
- This recombinant monoclonal antibody can detects endogenous levels of CD27 protein.
- Formulation:
- Phosphate-buffered solution
- Source:
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- Dilution:
- ELISA 1:5000-100000;FCM 1-2μg/Test
- Purification:
- Recombinant Expression and Affinity purified
- Concentration:
- Please check the information on the tube
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name:
- CD 27 antibody;CD27 antibody;CD27 antigen antibody;CD27 molecule antibody;CD27_HUMAN antibody;CD27L receptor antibody;LPFS2 antibody;MGC20393 antibody;OTTHUMP00000238557 antibody;S152 antibody;T cell activation antigen CD27 antibody;T cell antivation antigen S152 antibody;T-cell activation antigen CD27 antibody;T14 antibody;TNFRSF 7 antibody;TNFRSF7 antibody;TNFSF7 antibody;Tp 55 antibody;Tp55 antibody;Tumor necrosis factor receptor superfamily member 7 antibody;CD27 nanobody;
- Background:
- CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]
- Function:
- Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
- Subcellular Location:
- Membrane; Single-pass type I membrane protein.
- Expression:
- Found in most T-lymphocytes.
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