CD3 (PN0632) Nb-FC recombinant antibody

  • Catalog No.：YA0261
  • Applications：ELISA;FCM
  • Reactivity：Human
    • Target：
    • CD3
    • Gene Name：
    • CD3E T3E
    • Protein Name：
    • T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
    • Human Gene Id：
    • 916
    • Human Swiss Prot No：
    • P07766
    • Immunogen：
    • Purified recombinant Human CD3
    • Specificity：
    • This recombinant monoclonal antibody can detects endogenous levels of CD3 protein.
    • Formulation：
    • Phosphate-buffered solution
    • Source：
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution：
    • ELISA 1:5000-100000 FCM 1-2μg/Test
    • Purification：
    • Recombinant Expression and Affinity purified
    • Concentration：
    • Please check the information on the tube
    • Storage Stability：
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name：
    • T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e);CD3 nanobody;
    • Background：
    • The protein encoded byThis gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects inThis gene cause immunodeficiency.This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
    • Function：
    • The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
    • Subcellular Location：
    • Cell membrane ; Single-pass type I membrane protein .
    • Expression：
    • Membranous

    Attributes

    • Code：
    • YA0261
    • Size
    • 40μg / 100μg / 200μg
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-11-25
    Order

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