• Target：
• CD325

• Gene Name：
• CDH2 CDHN NCAD

• Protein Name：
• Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)

• Human Gene Id：
• 1000

• Human Swiss Prot No：
• P19022

• Immunogen：
• Purified recombinant Human CD325

• Specificity：
• This recombinant monoclonal antibody can detects endogenous levels of CD325 protein.

• Formulation：
• Phosphate-buffered solution

• Source：
• Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

• Dilution：
• ELISA 1:5000-100000;FCM 1-2μg/Test

• Purification：
• Recombinant Expression and Affinity purified

• Concentration：
• Please check the information on the tube

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• CADH2_HUMAN antibody;Cadherin 2 antibody;Cadherin 2 N cadherin neuronal antibody;Cadherin 2 type 1 antibody;Cadherin 2 type 1 N cadherin neuronal antibody;Cadherin 2;type 1;N-cadherin (neuronal) antibody;Cadherin-2 antibody;Cadherin2 antibody;Calcium dependent adhesion protein neuronal antibody;CD325 antibody;CD325 antigen antibody;CDH2 antibody;CDHN antibody;CDw325 antibody;CDw325 antigen antibody;N cadherin 1 antibody;N-cadherin antibody;NCAD antibody;Neural cadherin antibody;OTTHUMP00000066304 antibody;OTTHUMP00000067378 antibody;CD325 nanobody;

• Background：
• This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein.This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]

• Function：
• Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein . Cell membrane, sarcolemma . Cell junction . Cell surface . Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes. .

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