CD34 (PN0492) Nb-FC recombinant antibody

  • Catalog No.:YA0322
  • Applications:FCM;ELISA
  • Reactivity:Human
    • Target:
    • CD34
    • Gene Name:
    • CD34
    • Protein Name:
    • Hematopoietic progenitor cell antigen CD34 (CD antigen CD34)
    • Human Gene Id:
    • 947
    • Human Swiss Prot No:
    • P28906
    • Immunogen:
    • Purified recombinant Human CD34
    • Specificity:
    • This recombinant monoclonal antibody can detects endogenous levels of CD34 protein.
    • Formulation:
    • Phosphate-buffered solution
    • Source:
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution:
    • ELISA 1:5000-100000;FCM 1-2μg/Test
    • Purification:
    • Recombinant Expression and Affinity purified
    • Concentration:
    • Please check the information on the tube
    • Storage Stability:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name:
    • CD34 antibody;CD34 antigen antibody;CD34 molecule antibody;CD34_HUMAN antibody;Cluster designation 34 antibody;cluster of differentiation 34 antibody;Hematopoietic progenitor cell antigen CD34 antibody;HPCA1 antibody;Mucosialin antibody;OTTHUMP00000034733 antibody;OTTHUMP00000034734 antibody;CD34 nanobody;
    • Background:
    • The protein encoded byThis gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells.This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Aug 2011]
    • Function:
    • alternative products:Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.,
    • Subcellular Location:
    • Membrane; Single-pass type I membrane protein.
    • Expression:
    • Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.