• Target：
• IL-2

• Gene Name：
• IL2

• Protein Name：
• Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)

• Human Gene Id：
• 3558

• Human Swiss Prot No：
• P60568

• Immunogen：
• Purified recombinant Human IL-2

• Specificity：
• This recombinant monoclonal antibody can detects endogenous levels of IL-2 protein.

• Formulation：
• Phosphate-buffered solution

• Source：
• Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

• Dilution：
• ELISA 1:5000-100000

• Purification：
• Recombinant Expression and Affinity purified

• Concentration：
• Please check the information on the tube

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• IL2;Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin;IL-2 nanobody;

• Background：
• The protein encoded byThis gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor ofThis cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression ofThis gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role ofThis gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]

• Function：
• disease:A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.,Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.,online information:Interleukin-2 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.,similarity:Belongs to the IL-2 family.,

• Subcellular Location：
• Secreted.

• Expression：
• Blood,PCR rescued clones,Placenta,Spleen

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