• Target：
• NKp80

• Gene Name：
• KLRF1 CLEC5C ML

• Protein Name：
• Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80) (C-type lectin domain family 5 member C)

• Human Gene Id：
• 51348

• Human Swiss Prot No：
• Q9NZS2

• Immunogen：
• Purified recombinant Human NKp80

• Specificity：
• This recombinant monoclonal antibody can detects endogenous levels of NKp80 protein.

• Formulation：
• Phosphate-buffered solution

• Source：
• Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

• Dilution：
• ELISA 1:5000-100000 FCM 1-2μg/Test

• Purification：
• Recombinant Expression and Affinity purified

• Concentration：
• Please check the information on the tube

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• NKp80;CLEC5C;NKp80 nanobody;

• Background：
• KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]

• Function：
• Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.,online information:KLRF1,similarity:Contains 1 C-type lectin domain.,subunit:Homodimer.,tissue specificity:Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes.,

• Subcellular Location：
• Membrane ; Single-pass type II membrane protein .

• Expression：
• Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes.

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