Recombinant Human EGFR protein ,C- His tag

  • Catalog No.：YD2235
  • Reactivity：Human
    • Purity：
    • >90% as determined by SDS-PAGE
    • In Vivo：
    • < 1.0 EU per μg of the protein as determined by the LAL method.
    • Sequence：
    • A DNA sequence encoding the human EGFR(Met1-Ser645) was fused with the C-terminal His tag
    • Human Swiss Prot No：
    • P00533
    • Formulation：
    • Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.
    • Source：
    • Mammalian cells
    • Dilution：
    • Reconstitute in sterile water for a stock solution
    • Concentration：
    • >90% as determined by SDS-PAGE
    • Storage Stability：
    • Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
    • Other Name：
    • ERBB, ERBB1, HER1
    • Subcellular Location：
    • Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536, PubMed:17909029). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055). .; [Isoform 2]: Secreted.
    • Expression：
    • Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.

    Attributes

    • Code：
    • YD2235
    • Size
    • 100μg / 1mg
    • Price$：
    • 570 / 3420
    • Delivery：
    • 2025-01-10
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