• Purity：
• >90% as determined by SDS-PAGE

• Gene Name：
• C5AR1

• Protein Name：
• C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)

• Sequence：
• Amino acid:1-37,with FC tag.

• Human Gene Id：
• 728

• Human Swiss Prot No：
• P21730

• Formulation：
• Phosphate-buffered solution

• Source：
• Mammalian cells

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• C5a anaphylatoxin chemotactic receptor 1 ;C5a anaphylatoxin chemotactic receptor;C5a-R;C5aR;CD antigen CD88;C5AR1;C5AR;C5R1;

• Function：
• Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:10636859, PubMed:15153520, PubMed:1847994, PubMed:29300009, PubMed:7622471, PubMed:8182049, PubMed:9553099). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:7622471, PubMed:8182049, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Note=Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .

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