• Purity：
• >90% as determined by SDS-PAGE

• Gene Name：
• CD226

• Protein Name：
• CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)

• Sequence：
• Amino acid:19-254,with FC tag.

• Human Gene Id：
• 10666

• Human Swiss Prot No：
• Q15762

• Formulation：
• Phosphate-buffered solution

• Source：
• Mammalian cells

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• CD226 antigen ;DNAX accessory molecule 1;DNAM-1;CD antigen CD226;CD226;DNAM1;

• Function：
• Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein .

• Expression：
• Expressed by peripheral blood T-lymphocytes.

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