CD40-FC recombinant protein

  • Catalog No.:YD3066
  • Reactivity:Human;
    • Purity:
    • >90% as determined by SDS-PAGE
    • Gene Name:
    • CD40
    • Protein Name:
    • Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
    • Sequence:
    • Amino acid:21-193,with FC tag.
    • Human Gene Id:
    • 958
    • Human Swiss Prot No:
    • P25942
    • Formulation:
    • Phosphate-buffered solution
    • Source:
    • Mammalian cells
    • Storage Stability:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name:
    • Tumor necrosis factor receptor superfamily member 5 ;B-cell surface antigen CD40;Bp50;CD40L receptor;CDw40;CD antigen CD40;CD40;TNFRSF5;
    • Function:
    • Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
    • Subcellular Location:
    • [Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.
    • Expression:
    • B-cells and in primary carcinomas.