CD40-FC recombinant protein
- Catalog No.:YD3066
- Reactivity:Human;
- Purity:
- >90% as determined by SDS-PAGE
- Protein Name:
- Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
- Sequence:
- Amino acid:21-193,with FC tag.
- Formulation:
- Phosphate-buffered solution
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name:
- Tumor necrosis factor receptor superfamily member 5 ;B-cell surface antigen CD40;Bp50;CD40L receptor;CDw40;CD antigen CD40;CD40;TNFRSF5;
- Function:
- Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
- Subcellular Location:
- [Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.
- Expression:
- B-cells and in primary carcinomas.