CD28-FC recombinant protein

  • Catalog No.：YD3067
  • Reactivity：Human;
    • Purity：
    • >90% as determined by SDS-PAGE
    • Gene Name：
    • CD28
    • Protein Name：
    • T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28)
    • Sequence：
    • Amino acid:19-152,with FC tag.
    • Human Gene Id：
    • 940
    • Human Swiss Prot No：
    • P10747
    • Formulation：
    • Phosphate-buffered solution
    • Source：
    • Mammalian cells
    • Storage Stability：
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name：
    • T-cell-specific surface glycoprotein CD28 ;TP44;CD antigen CD28;CD28;
    • Function：
    • Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).
    • Subcellular Location：
    • Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface .
    • Expression：
    • Expressed in T-cells and plasma cells, but not in less mature B-cells.

    Attributes

    • Code：
    • YD3067
    • Size
    • 5μg / 50μg / 500μg
    • Price$：
    • 52 / 272 / 1356
    • Delivery：
    • 2024-12-26
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