CD57-FC recombinant protein

  • Catalog No.:YD3084
  • Reactivity:Human;
    • Purity:
    • >90% as determined by SDS-PAGE
    • Gene Name:
    • B3GAT1
    • Protein Name:
    • Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 1) (Glucuronosyltransferase P) (GlcAT-P) (UDP-GlcUA:glycoprotein beta-1,3-glucuronylt
    • Human Swiss Prot No:
    • Q9P2W7
    • Formulation:
    • Phosphate-buffered solution
    • Source:
    • Mammalian cells
    • Storage Stability:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name:
    • Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 ;EC 2.4.1.135;Beta-1,3-glucuronyltransferase 1;Glucuronosyltransferase P;GlcAT-P;UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase;GlcUAT-P;B3GAT1;GLCATP;
    • Function:
    • Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
    • Subcellular Location:
    • [Isoform 1]: Golgi apparatus membrane ; Single-pass type II membrane protein . Secreted .; [Isoform 2]: Golgi apparatus membrane ; Single-pass type II membrane protein . Endoplasmic reticulum membrane . Secreted .
    • Expression:
    • Mainly expressed in the brain.