EEA1 rabbit-FC recombinant protein
- Catalog No.：YD3139
- Reactivity：Human;
- Purity：
- >90% as determined by SDS-PAGE
- Protein Name：
- Early endosome antigen 1
- Sequence：
- Amino acid:1201-1411,with rabbit FC tag.
- Formulation：
- Phosphate-buffered solution
- Storage Stability：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name：
- EEA1;ZFYVE2;Early endosome antigen 1;Endosome-associated protein p162;Zinc finger FYVE domain-containing protein 2
- Background：
- disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,
- Function：
- disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,
- Subcellular Location：
- Cytoplasm. Early endosome membrane; Peripheral membrane protein.
- Expression：
- Aorta,Cervix carcinoma,Fetal brain cortex,Skeletal muscle,
