β-actin Monoclonal Antibody(5B7), AbFluor 594 Conjugated

  • Catalog No.：YM2189
  • Applications：IF;WB;IHC
  • Reactivity：Human;Rat;Mouse;Mk;Dg;Ch;Hamster;Rabbit;Insect
    • Target：
    • Actin β
    • Fields：
    • >>Rap1 signaling pathway;>>Phagosome;>>Apoptosis;>>Hippo signaling pathway;>>Focal adhesion;>>Adherens junction;>>Tight junction;>>Platelet activation;>>Neutrophil extracellular trap formation;>>Leukocyte transendothelial migration;>>Thermogenesis;>>Regulation of actin cytoskeleton;>>Thyroid hormone signaling pathway;>>Oxytocin signaling pathway;>>Gastric acid secretion;>>Amyotrophic lateral sclerosis;>>Bacterial invasion of epithelial cells;>>Vibrio cholerae infection;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Salmonella infection;>>Yersinia infection;>>Influenza A;>>Proteoglycans in cancer;>>Hepatocellular carcinoma;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy;>>Viral myocarditis;>>Fluid shear stress and atherosclerosis
    • Gene Name：
    • ACTB
    • Protein Name：
    • Actin cytoplasmic 1
    • Human Gene Id：
    • 60
    • Human Swiss Prot No：
    • P60709
    • Specificity：
    • β-actin Monoclonal Antibody(5B7) AbFluor™ 594 Conjugated specially designed for your Immunofluorescence analysis.
    • Formulation：
    • Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
    • Source：
    • Monoclonal, Mouse IgG1
    • Dilution：
    • Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:200, IF 1:200.
    • Purification：
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1mg/ml
    • Storage Stability：
    • Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezi
    • Other Name：
    • ACTB;Actin; cytoplasmic 1;Beta-actin;Actin β;β-Actin;Beta actin;B actin;actin Beta;
    • Background：
    • This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008],
    • Function：
    • disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the
    • Subcellular Location：
    • Cytoplasm, cytoskeleton . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
    • Expression：
    • B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car

    Attributes

    • Code：
    • YM2189
    • Size
    • 50μL / 100μL / 500μL
    • Price$：
    • 112 / 192 / 840
    • Delivery：
    • 2024-12-08
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