• Target：
• CD27

• Gene Name：
• CD27 TNFRSF7

• Protein Name：
• CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)

• Human Gene Id：
• 939

• Human Swiss Prot No：
• P26842

• Immunogen：
• Purified recombinant Human CD27

• Specificity：
• This recombinant monoclonal antibody can detects endogenous levels of CD27 protein.

• Formulation：
• Phosphate-buffered solution

• Source：
• Monoclonal,Mouse,IgG1,kappa

• Dilution：
• ELISA 1:5000-100000;FCM 1-2μg/Test

• Purification：
• Recombinant Expression and Affinity purified

• Concentration：
• Please check the information on the tube

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• CD 27 antibody;CD27 antibody;CD27 antigen antibody;CD27 molecule antibody;CD27_HUMAN antibody;CD27L receptor antibody;LPFS2 antibody;MGC20393 antibody;OTTHUMP00000238557 antibody;S152 antibody;T cell activation antigen CD27 antibody;T cell antivation antigen S152 antibody;T-cell activation antigen CD27 antibody;T14 antibody;TNFRSF 7 antibody;TNFRSF7 antibody;TNFSF7 antibody;Tp 55 antibody;Tp55 antibody;Tumor necrosis factor receptor superfamily member 7 antibody;CD27 nanobody;

• Background：
• CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]

• Function：
• Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

• Subcellular Location：
• Membrane; Single-pass type I membrane protein.

• Expression：
• Found in most T-lymphocytes.

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