Actin pan (PT0145R) rabbit mAb
- Catalog No.:YM8082
- Applications:WB;IHC;IF;IP;ELISA
- Reactivity:Human; Mouse; Rat;
- Target:
- Actin skeletal muscle α
- Gene Name:
- Actin-pan
- Protein Name:
- Actin pan
- Human Gene Id:
- 58
- Human Swiss Prot No:
- P62736/P68032/P60709/P63261/P68133/P63267
- Mouse Gene Id:
- 11459
- Mouse Swiss Prot No:
- P68134
- Rat Gene Id:
- 29437
- Rat Swiss Prot No:
- P68136
- Specificity:
- endogenous
- Formulation:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source:
- Monoclonal, rabbit, IgG, Kappa
- Dilution:
- IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
- Purification:
- Protein A
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Actin, alpha cardiac muscle 1;Alpha-cardiac actin;ACTC;Actin, alpha skeletal muscle;Alpha-actin-1;ACTA1;Actin, aortic smooth muscle;Alpha-actin-2;ACTA2;ACTSA, ACTVS;Actin, cytoplasmic 1;Beta-actin;ACTB;Actin, cytoplasmic 2;Gamma-actin;ACTG1;ACTG;Actin, gamma-enteric smooth muscle;Alpha-actin-3;Gamma-2-actin;Smooth muscle gamma-actin;ACTA3, ACTL3, ACTSG;ACTG2
- Molecular Weight(Da):
- 42kD
- Observed Band(KD):
- 42kD
- Background:
- This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008],
- Function:
- disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the
- Subcellular Location:
- Cytoplasmic, Membranous
- Expression:
- B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car
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- Antibody-FAQs
- Products Images
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Actin pan(PT0145R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: C6 Lane 2: Hela Lane 3: PC-12 Lane 4: RAW264.7 Predicted band size: 42kDa Observed band size: 42kDa
- Mouse heart was stained with Anti-Actin pan (PT0145R) rabbit antibody
- Rat heart was stained with Anti-Actin pan (PT0145R) rabbit antibody
- Human skeletal muscle was stained with Anti-Actin pan (PT0145R) rabbit antibody