• Target：
• Actin skeletal muscle α

• Gene Name：
• Actin-pan

• Protein Name：
• Actin pan

• Human Gene Id：
• 58

• Human Swiss Prot No：
• P62736/P68032/P60709/P63261/P68133/P63267

• Mouse Gene Id：
• 11459

• Mouse Swiss Prot No：
• P68134

• Rat Gene Id：
• 29437

• Rat Swiss Prot No：
• P68136

• Specificity：
• endogenous

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Monoclonal, rabbit, IgG, Kappa

• Dilution：
• IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

• Purification：
• Protein A

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Actin, alpha cardiac muscle 1;Alpha-cardiac actin;ACTC;Actin, alpha skeletal muscle;Alpha-actin-1;ACTA1;Actin, aortic smooth muscle;Alpha-actin-2;ACTA2;ACTSA, ACTVS;Actin, cytoplasmic 1;Beta-actin;ACTB;Actin, cytoplasmic 2;Gamma-actin;ACTG1;ACTG;Actin, gamma-enteric smooth muscle;Alpha-actin-3;Gamma-2-actin;Smooth muscle gamma-actin;ACTA3, ACTL3, ACTSG;ACTG2

• Molecular Weight(Da)：
• 42kD

• Observed Band(KD)：
• 42kD

• Background：
• This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008],

• Function：
• disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the

• Subcellular Location：
• Cytoplasmic, Membranous

• Expression：
• B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car

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