Tra-2α Polyclonal Antibody

    • Catalog No.:YT4713
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • Tra-2α
      • Fields:
      • >>Spliceosome;>>Alcoholic liver disease
      • Gene Name:
      • TRA2A
      • Protein Name:
      • Transformer-2 protein homolog alpha
      • Human Swiss Prot No:
      • Q13595
      • Mouse Swiss Prot No:
      • Q6PFR5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human TRA-2 alpha. AA range:221-270
      • Specificity:
      • Tra-2α Polyclonal Antibody detects endogenous levels of Tra-2α protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • TRA2A;Transformer-2 protein homolog alpha;TRA-2 alpha;TRA2-alpha;Transformer-2 protein homolog A
      • Observed Band(KD):
      • 33kD
      • Background:
      • This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],
      • Function:
      • function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.,PTM:Phosphorylated in the RS domains.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Cervix carcinoma,Epithelium,Hepatocyte,Lung,Testis,Uterus,
      • Products Images
      • Western Blot analysis of various cells using Tra-2α Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
      • Immunofluorescence analysis of HeLa cells, using TRA-2 alpha Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TRA-2 alpha Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HUVEC cells, using TRA-2 alpha Antibody. The lane on the right is blocked with the synthesized peptide.