FSH (ABT172) IHC kit
- Catalog No.:IHCM6874
- Applications:IHC
- Reactivity:Human;
- Target:
- FSH
- Fields:
- >>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction;>>GnRH signaling pathway;>>Ovarian steroidogenesis
- Gene Name:
- FSHB
- Protein Name:
- FSH
- Human Gene Id:
- 2488
- Human Swiss Prot No:
- P01225
- Immunogen:
- Synthesized peptide derived from human FSH AA range: 1-100
- Specificity:
- The antibody can specifically recognize human FS H protein, and shows no cross reaction with LH, CG and TSH proteins.
- Source:
- Mouse, Monoclonal/IgG2a, kappa
- Purification:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- Storage Stability:
- 2°C to 8°C/1 year
- Other Name:
- Follitropin subunit beta (Follicle-stimulating hormone beta subunit;FSH-B;FSH-beta;Follitropin beta chain)
- Background:
- follicle stimulating hormone beta subunit(FSHB) Homo sapiens The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
- Function:
- disease:Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [MIM:229070]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men.,function:Stimulates development of follicle and spermatogenesis in the reproductive organs.,online information:Follicle-stimulating hormone entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the names Gonal-F or Metrodin HP (Serono) and Puregon (Organon). Used in the treatment of infertility in women with proven hypopituitarism or who have not responded to clomifene; or in superovulation treatment for assisted conception (such as in vitro fertilization). Metrodin HP is also used in the treatment of hypogona
- Subcellular Location:
- Cytoplasmic
- Expression:
- Cytoplasmic
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- Antibody-FAQs
- Products Images
- Human pituitary adenoma tissue was stained with Anti-FSH (ABT172) Antibody
- Human pituitary adenoma tissue was stained with Anti-FSH (ABT172) Antibody