Phospho EPHA2/3/4 (Y588/596) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA1453C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- EPHA2/3/4
- Human Swiss Prot No:
- P29317/P29320/P54764
- Storage Stability:
- 2-8°C/6 months
- Detection Method:
- Colorimetric
- Function:
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, phosphorylation, neuron differentiation, ephrin receptor signaling pathway,
- Subcellular Location:
- Cell membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and perinuclear regions in cancer cells (PubMed:18794797). .
- Expression:
- Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary.
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