Phospho Casein Kinase I α (Y321) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA1528C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- CSNK1A1
- Human Gene Id:
- 1452
- Human Swiss Prot No:
- P48729
- Mouse Swiss Prot No:
- Q8BK63
- Rat Swiss Prot No:
- P97633
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex.,
- Function:
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, phosphorylation,
- Subcellular Location:
- Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome, centromere, kinetochore . Nucleus speckle . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, spindle . Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688). .
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