Phospho SEK1/MKK4 (T261) Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA1651C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • MAP2K4
    • Human Gene Id:
    • 6416
    • Human Swiss Prot No:
    • P45985
    • Mouse Swiss Prot No:
    • P47809
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).,PTM:Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with SPAG9.,tissue specificity:Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.,
    • Function:
    • MAPKKK cascade, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process,intracellular signaling cascade, protein kinase cascade, JNK cascade, phosphorylation, stress-activated protein kinase signaling pathway, cellular response to stress,
    • Subcellular Location:
    • Cytoplasm . Nucleus .
    • Expression:
    • Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.