Total UBA2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3424C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • UBA2
    • Human Swiss Prot No:
    • Q9UBT2
    • Mouse Swiss Prot No:
    • Q9Z1F9
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • SUMO-activating enzyme subunit 2 (EC 6.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:The dimeric enzyme acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.,pathway:Protein modification; protein sumoylation.,similarity:Belongs to the ubiquitin-activating E1 family.,subunit:Heterodimer of SAE1 and SAE2. The complex binds SUMO proteins via SAE2.,
    • Function:
    • proteolysis, macromolecule catabolic process, modification-dependent protein catabolic process, protein catabolic process, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process, proteolysis involved in cellular protein catabolic process,
    • Subcellular Location:
    • Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.