Total JMJD2B Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3502C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • KDM4B
    • Human Swiss Prot No：
    • O94953
    • Mouse Swiss Prot No：
    • Q91VY5
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Lysine-specific demethylase 4B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B)
    • Detection Method：
    • Colorimetric
    • Background：
    • cofactor:Binds 1 Fe(2+) ion per subunit.,domain:The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,similarity:Contains 2 PHD-type zinc fingers.,similarity:Contains 2 Tudor domains.,
    • Function：
    • chromatin organization, transcription, chromatin modification, regulation of transcription, chromosome organization,oxidation reduction,
    • Subcellular Location：
    • Nucleus .

    Attributes

    • Code：
    • KA3502C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-10
    Order

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